Discoloration Defense Serum
VersusiS Clinical Moisturising Complex

iS Clinical Moisturising Complex
Best For
Individuals looking to reduce dark spots and improve skin tone.
Best For
All skin types, dehydrated skin, irritated skin, post-procedure.
Ingredient Profiles
Discoloration Defense Serum
- • Aqua
- • Butylene Glycol
- • Niacinamide
- • Hydroxyethylpiperazine Ethane Sulfonic Acid
- • Glycerin
- • Hydroxyethyl Urea
- • Propylene Glycol
- • Tranexamic Acid
- • Phenoxyethanol
- • Caprylyl Glycol
- • Allantoin
- • Chlorphenesin
- • Xanthan Gum
- • Disodium EDTA
SkinCeuticals' Discoloration Defense Serum is a dark spot corrector that is clinically proven to reduce the appearance of skin discolouration. Clinical studies have demonstrated the efficacy of tranexamic acid and niacinamide in treating post-inflammatory hyperpigmentation and improving skin tone. For more information, refer to the following studies: An Investigator-Developed Regimen for Treatment and Prevention of Post-Inflammatory Hyperpigmentation in Skin of Color and Real World Case Series: Integrated Skincare With Advanced RGN-6 Serum.
iS Clinical Moisturising Complex
- • Water
- • Hyaluronic Acid
- • Glycerin
- • Butylene Glycol
- • Dimethicone
- • Glyceryl Stearate
- • PEG-100 Stearate
- • Panthenol
- • Squalane
- • Caprylic-Capric Triglyceride
- • Tocopherol
- • Panthenyl Triacetate
- • Ethyl Linoleate
The iS Clinical Moisturising Complex is an intensively hydrating moisturizer formulated with powerful botanicals, natural vitamins, and essential bionutrients. This formula is designed to support a protective barrier against environmental stressors while providing both deep and surface hydration. Suitable for all skin types and ages, it effectively smooths and softens the skin, making it an ideal choice for daily use.
Evidence-Based Efficacy
Research indicates that maintaining skin barrier function is crucial for preventing irritant and allergic contact dermatitis, which can be supported by effective moisturizers like the iS Clinical Moisturising Complex. For more information, see the studies: Skin Barrier Biomarkers in Patch-Induced and Clinical Allergic and Irritant Contact Dermatitis and Cannabidiol in Skin Health: A Comprehensive Review of Topical Applications in Dermatology and Cosmetic Science.
Safety & Application
Directions
Twice daily, apply 3-5 drops of this skin discolouration serum to the face. If using in the morning, apply after a SkinCeuticals vitamin C serum and follow with a SkinCeuticals broad spectrum SPF 30+ sunscreen. Limit sun exposure while using this product.
Safety Notice
For external use only. Avoid contact with eyes. Keep out of reach of children.
Directions
Apply a small amount to clean skin, smoothing evenly over face and neck.
Safety Notice
For external use only. Avoid contact with eyes. If irritation occurs, discontinue use.



