iS Clinical Hydra-Cool Serum
VersusObagi 0.5 Smoothing Retinol
Best For
All skin types, dehydrated skin, acne, mild sunburn, redness, irritation, aging skin.
Best For
Normal to Oily, Normal to Dry, Combination skin types.
Ingredient Profiles
iS Clinical Hydra-Cool Serum
- • Water
- • Sodium Hyaluronate
- • Pantothenic Acid
- • Pentylene Glycol
- • Asiaticoside
- • Asiatic Acid
- • Madecassic Acid
Hydra-Cool Serum is formulated to rejuvenate, hydrate, and visibly soothe the skin. This refreshing, powerful serum combines superior antioxidants with essential botanicals and bionutrients. Hydra-Cool Serum is designed for all skin types and for all ages, and is gentle enough for even the most sensitive skin.
Evidence-Based Efficacy
The efficacy of various ingredients in skincare formulations has been supported by numerous studies. For instance, the role of bioactive compounds in cosmetics, including their potential to combat skin aging and enhance hydration, is discussed in the study titled Algae a Potential Source in Cosmetics: Current Status, Challenges, and Economic Implications. Additionally, the importance of fluid volume estimation in skin health is highlighted in the study Fluid Volume Estimation by Bioimpedance: Methodological Caveats and Clinical Interpretation.
Obagi 0.5 Smoothing Retinol
- • Retinol
- • Ascorbic Acid
- • Calendula Officinalis Flower Extract
- • Camellia Sinensis Leaf Extract
- • Chamomilla Recutita Flower Extract
- • Dipotassium Glycyrrhizate
- • Sodium Hyaluronate
- • Tocopheryl Acetate
Obagi 0.5 Smoothing Retinol is a cream-based formula designed to renew your skin effectively. This potent yet gentle retinol helps to resurface the skin, minimizing the appearance of fine lines and wrinkles while promoting skin turnover. Ideal for normal to oily, normal to dry, and combination skin types.
Evidence-Based Efficacy
Research supports the efficacy of retinol in promoting skin renewal and reducing signs of aging. For more information, see the following studies: Retinol and Skin Aging, Effects of Retinol on Skin.
Safety & Application
Directions
Apply a small amount to the palm of hand. Using fingertips, dab and smooth evenly over face and neck. Serum may be used by itself or layered with other [iS Clinical](/brands/isclinical) products.
Safety Notice
For external use only. Avoid contact with eyes. Keep out of reach of children. If irritation occurs, discontinue use.
Directions
Uncap the airless pump and apply 1 pump, or a pearl-sized amount to your face. Massage until fully absorbed. Use once daily in the evenings.
Safety Notice
When using this product, you may experience mild [redness](/concerns/redness), peeling, or skin irritation. These are normal, temporary indications the product is working. If irritation occurs, limit use to every other night, or as tolerated. Daily use of a broad spectrum sunscreen with an SPF of 30 or higher is highly recommended.
