Clinical Evidence on Dipotassium Glycyrrhizate

Efficacy in Xerosis Treatment

Dipotassium Glycyrrhizate has shown significant efficacy in improving skin hydration and barrier function in individuals with xerosis. A study demonstrated that a topical formulation containing this ingredient improved hydration levels and reduced transepidermal water loss (TEWL) after 28 days of application. For more details, refer to the study titled Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis.

Post-Photorejuvenation Recovery

In another study, Dipotassium Glycyrrhizate was included in a platinum-liposome-based facial mask aimed at soothing skin irritation post-photorejuvenation. The results indicated significant improvements in skin hydration and reduced irritation, showcasing its effectiveness in post-procedural skincare. For further insights, see A Split-Face Randomized Study on the Efficacy of a Platinum-Liposome-Based Facial Mask.

Role in Diabetic Wound Healing

Dipotassium Glycyrrhizate has also been explored in the context of diabetic wound healing. A hydrogel incorporating this ingredient demonstrated enhanced healing properties by modulating the inflammatory environment, thus promoting recovery in diabetic wounds. More information can be found in the study titled A upper critical solution temperature- and synergistic antioxidant-responsive tremella polysaccharide hydrogel for enhancing diabetic wound healing.