Clinical Evidence

Prevention of Atopic Dermatitis in High-Risk Infants

Growing evidence highlights the role of physiological lipids in maintaining skin barrier function and preventing atopic dermatitis (AD). Current evidence on the efficacy, safety, and clinical relevance of stratum corneum (SC) lipid-based therapies to prevent AD and increase skin barrier integrity in high-risk infants was reviewed. These therapies were reported to replenish deficient SC lipids, thereby improving skin barrier function, a critical aspect of AD management. Prevention of Atopic Dermatitis in High-Risk Infants: A Review of the Role of Lipid-Based Barrier Repair Therapy

Addressing the Structural Organization of Silicone Alternatives

The study introduces a computational methodology to aid the research of silicone alternatives, including Pentaerythrityl Tetraethylhexanoate, disclosing their structural performance in formulations. This research is crucial for developing natural and sustainable replacements for synthetic compounds in cosmetics. Addressing the Structural Organization of Silicone Alternatives in Formulations by Molecular Dynamics Simulations and a Novel Equilibration Protocol

One-Pot Method of Synthesizing TEMPO-Oxidized Bacterial Cellulose Nanofibers

In skincare, bio-based polymers like TEMPO-oxidized bacterial cellulose nanofibers show promise due to their unique properties. This research highlights innovative methods for synthesizing such materials, which can complement the use of Pentaerythrityl Tetraethylhexanoate in formulations. One-Pot Method of Synthesizing TEMPO-Oxidized Bacterial Cellulose Nanofibers Using Immobilized TEMPO for Skincare Applications