iS Clinical Hydra-Cool Serum
VersusObagi Retinol 1.0 Cream
Best For
All skin types, dehydrated skin, acne, mild sunburn, redness, irritation, aging skin.
Best For
Acne & Blemish, Aging & Sagging, Fine Lines & Wrinkles, Skin Discoloration
Ingredient Profiles
iS Clinical Hydra-Cool Serum
- • Water
- • Sodium Hyaluronate
- • Pantothenic Acid
- • Pentylene Glycol
- • Asiaticoside
- • Asiatic Acid
- • Madecassic Acid
Hydra-Cool Serum is formulated to rejuvenate, hydrate, and visibly soothe the skin. This refreshing, powerful serum combines superior antioxidants with essential botanicals and bionutrients. Hydra-Cool Serum is designed for all skin types and for all ages, and is gentle enough for even the most sensitive skin.
Evidence-Based Efficacy
The efficacy of various ingredients in skincare formulations has been supported by numerous studies. For instance, the role of bioactive compounds in cosmetics, including their potential to combat skin aging and enhance hydration, is discussed in the study titled Algae a Potential Source in Cosmetics: Current Status, Challenges, and Economic Implications. Additionally, the importance of fluid volume estimation in skin health is highlighted in the study Fluid Volume Estimation by Bioimpedance: Methodological Caveats and Clinical Interpretation.
Obagi Retinol 1.0 Cream
Obagi Retinol 1.0 Cream is a highly effective slow-release retinol formulation designed to promote skin turnover, helping to even skin tone and minimize signs of aging such as fine lines and wrinkles. This cream is suitable for normal to oily, normal to dry, and combination skin types, providing visible improvements in skin texture with minimal irritation. Clinical studies have shown that retinol can significantly improve skin texture and reduce the appearance of fine lines and wrinkles. For more information, refer to the Abstracts of Poster Presentations: MauiDerm 2017.
Safety & Application
Directions
Apply a small amount to the palm of hand. Using fingertips, dab and smooth evenly over face and neck. Serum may be used by itself or layered with other [iS Clinical](/brands/isclinical) products.
Safety Notice
For external use only. Avoid contact with eyes. Keep out of reach of children. If irritation occurs, discontinue use.
Directions
Uncap the airless pump and apply 1 pump, or a pearl-sized amount to your face. Massage until fully absorbed. Use once daily in the evenings.
Safety Notice
When using this product, you may experience mild [redness](/concerns/redness), peeling, or skin irritation. These are normal, temporary indications the product is working. If irritation occurs, limit use to every other night, or as tolerated. Daily use of a broad spectrum sunscreen with an SPF of 30 or higher is highly recommended.




