Hyaluronic Acid Intensifier Multi-Glycan
VersusObagi 0.5 Smoothing Retinol

Hyaluronic Acid Intensifier Multi-Glycan
Best For
Individuals looking to improve skin hydration, texture, and reduce the appearance of fine lines.
Best For
Normal to Oily, Normal to Dry, Combination skin types.
Ingredient Profiles
Hyaluronic Acid Intensifier Multi-Glycan
- • Hyaluronic Acid
- • Proxylane
- • Lactobacillus-Soybean Ferment Extract
- • Dipotassium Glycyrrhizate
- • Sodium Hyaluronate
HA Intensifier Multi-Glycan is a next-generation corrective serum proven to amplify the skin’s own hyaluronic acid levels, leaving the skin looking plumper and more contoured. Clinical studies have shown that this serum can hydrate the skin for up to 48 hours and improve facial volume and the appearance of fine lines. For more detailed evidence, refer to the studies available on Europe PMC.
Obagi 0.5 Smoothing Retinol
- • Retinol
- • Ascorbic Acid
- • Calendula Officinalis Flower Extract
- • Camellia Sinensis Leaf Extract
- • Chamomilla Recutita Flower Extract
- • Dipotassium Glycyrrhizate
- • Sodium Hyaluronate
- • Tocopheryl Acetate
Obagi 0.5 Smoothing Retinol is a cream-based formula designed to renew your skin effectively. This potent yet gentle retinol helps to resurface the skin, minimizing the appearance of fine lines and wrinkles while promoting skin turnover. Ideal for normal to oily, normal to dry, and combination skin types.
Evidence-Based Efficacy
Research supports the efficacy of retinol in promoting skin renewal and reducing signs of aging. For more information, see the following studies: Retinol and Skin Aging, Effects of Retinol on Skin.
Safety & Application
Directions
Once or twice daily, apply 4-6 drops to the palm of the hand and dab onto forehead, cheeks, chin, and neck. Blend the [hyaluronic acid](/ingredients/hyaluronic-acid) serum into skin. If using in the morning, apply after a [SkinCeuticals](/brands/skinceuticals) vitamin C antioxidant serum and before a SkinCeuticals sunscreen.
Safety Notice
Fragrance-free and suitable for use in between injectable treatments. Always consult a Medical Professional before aesthetic treatments.
Directions
Uncap the airless pump and apply 1 pump, or a pearl-sized amount to your face. Massage until fully absorbed. Use once daily in the evenings.
Safety Notice
When using this product, you may experience mild [redness](/concerns/redness), peeling, or skin irritation. These are normal, temporary indications the product is working. If irritation occurs, limit use to every other night, or as tolerated. Daily use of a broad spectrum sunscreen with an SPF of 30 or higher is highly recommended.



