Zinc PCA
Zinc Pyrrolidone Carboxylic AcidZinc PCA
Overview
Zinc PCA is a zinc salt of pyrrolidone carboxylic acid, recognized for its ability to regulate sebum production and provide anti-inflammatory benefits.
Clinical Evidence
Acne Management
Zinc PCA has been highlighted in the context of acne management, particularly in the publication The Role of Dermocosmetics in Acne Management: Asian Perspective. This study emphasizes the role of dermocosmetics containing active ingredients like Zinc PCA in improving tolerability and efficacy of acne treatments.
Scalp Conditions
In a cohort study, Zinc PCA was part of a treatment regimen for moderate to severe seborrheic dermatitis, showing significant improvement in symptoms such as dandruff and itchiness (A Cohort Clinical Study on the Efficacy of Topical Salicylic Acid/Piroctone Olamine Dandruff Pre-Gel and Cleanser in Improving Symptoms of Moderate to Severe Seborrheic Dermatitis of the Scalp).
Anti-Aging Properties
Zinc PCA is also noted for its antioxidant and collagen-preserving properties in formulations like Zeitgain cream, which aims to combat skin aging (Anti-Aging Properties of Ingredients Available in Zeitgain Cream).

