Clinical Evidence on Sodium Laureth Sulfate

Surfactants and Skin Irritation

Sodium Laureth Sulfate (SLES) is a surfactant that can cause skin irritation. A study titled Can Electrostatic Solvation Entropy Predict Skin Irritation Potential from Surfactants? discusses how the molecular structure of SLES influences its irritation potential through solvation thermodynamics.

TRPV1 Channel and Surfactants

Research titled The Role of TRPV1 Channel in Cosmetic Safety Evaluation highlights the relationship between SLES and the TRPV1 channel, indicating that traditional anionic surfactants like SLES can activate specific cellular responses that may lead to irritation.

Ocular Irritation in Baby Products

A comprehensive study titled From Safety Evaluation to Influencing Factors Analysis: A Comprehensive Investigation on Ocular Irritation of Baby Bath Products found that SLES had a high