Clinical Evidence on Polyquaternium-10

Dandruff Treatment

The study titled The Treatment and Evaluation of Dandruff and Scalp Erythema with Fermented Salix purpurea Bark Extract highlights the efficacy of shampoo formulations containing Polyquaternium-10 in reducing dandruff symptoms. The formulations were well tolerated and showed a reduction in dandruff visibility over 56 days.

Allergic Reactions

In a separate study, Two Cases of Allergic Contact Dermatitis Caused by Coco Betaine in Clobetasol Propionate Shampoo, it was noted that while Polyquaternium-10 is generally safe, other ingredients in formulations may cause allergic reactions, emphasizing the importance of ingredient awareness.

Antibacterial Properties

Research on Dialdehyde cellulose nanofibrils/polyquaternium stabilized ultra-fine silver nanoparticles for synergistic antibacterial therapy demonstrates that Polyquaternium-10 enhances antibacterial activity when combined with other agents, showcasing its potential in wound healing and infection prevention.