Clinical Evidence

Psoriasis Mechanism

Methylparaben is linked to psoriasis, an inflammatory skin disease. A study explored its mechanism using various scientific methods. Key findings include:

• Methylparaben targets identified through network toxicology.
• Core targets like INS, HIF1A, and PPARG influence inflammation and oxidative stress.
• Investigation of the potential mechanism by which methylparaben induces psoriasis.

Adverse Effects of Cosmetics

Methylparaben's use in cosmetics can lead to adverse effects, including contact dermatitis. The clinical significance of these effects is still being understood.

• Aspects of Adverse Effects of Cosmetic Products.

Topical Delivery in Dermatology

Methylparaben is used as a preservative in formulations like clobetasol propionate emulgel, enhancing efficacy while minimizing side effects.

• Development, characterization and in vitro evaluation of clobetasol propionate emulgel.