Clinical Evidence on Methyldihydrojasmonate

Atopic Dermatitis Prevention

Growing evidence highlights the role of physiological lipids in maintaining skin barrier function and preventing atopic dermatitis (AD). A review discusses lipid-based therapies that replenish deficient skin lipids, improving barrier function and hydration. However, evidence for preventing AD onset in infants remains limited, with trends toward reduced incidence noted. Prevention of Atopic Dermatitis in High-Risk Infants

Anti-Cancer Efficacy

Methyldihydrojasmonate has shown anti-cancer effects in studies targeting breast cancer cells. A transdermal microemulsion system was developed for effective delivery, demonstrating significant cytotoxicity against MCF-7 cell lines and notable tumor inhibition in vivo. Anti-tumor efficacy of an integrated methyl dihydrojasmonate transdermal microemulsion system

Safety Assessment

A safety assessment of methyl dihydrojasmonate has been conducted, ensuring its safe use in fragrance applications. RIFM fragrance ingredient safety assessment