Carbomer

Overview

Carbomer is a synthetic polymer widely used in cosmetic and pharmaceutical formulations as a thickening agent. It helps to stabilize emulsions and improve the texture of products.

Clinical Evidence

Health and Environmental Impacts

There is increasing concern regarding the impacts of personal care products (PCPs) on human health and the environment. A study discusses the implications of plastic particles in PCPs, including carbomer, and their contribution to pollution and health risks. For more details, see Plastic in dermatology: Impacts on human health, skin disease, and the contribution of personal care product use to environmental pollution.

Topical Drug Delivery

Carbomer has been utilized in the formulation of topical gels, such as voriconazole gel, which demonstrated effective drug delivery for treating dermatophytosis. The study highlights the stability and efficacy of carbomer-based formulations. For further reading, refer to Preparation and Optimization of Voriconazole Gel 0.25% for Topical Delivery in Terbinafine Resistance Dermatophytosis: In Vitro and Pilot Animal Study.

Treatment of Atopic Dermatitis

Research has shown that liquiritin carbomer gel can effectively alleviate symptoms of atopic dermatitis in mice. The gel demonstrated skin barrier protection and anti-inflammatory effects without significant toxicity. More information can be found in the study titled Ameliorative Effects of Liquiritin Carbomer Gel on Dinitrofluorobenzene-Induced Atopic Dermatitis in Mice.