iS Clinical Super Serum Advance+
VersusNeoStrata Skin Active FIRMING Potent Retinol Complex

iS Clinical Super Serum Advance+

NeoStrata Skin Active FIRMING Potent Retinol Complex
Best For
All skin types, especially those concerned with fine lines, wrinkles, and uneven skin tone.
Best For
Suitable for dry, normal, and oily skin types.
Ingredient Profiles
iS Clinical Super Serum Advance+
iS Clinical Super Serum Advance+
Super Serum Advance+ is a scientifically advanced, clinically proven formula that combines a 15% concentration of L-Ascorbic Acid (Vitamin C) with bioidentical Copper Tripeptide-1. This serum helps reduce the appearance of fine lines and wrinkles, improves the look of hypertrophic scars and fine stretch marks, and safely brightens uneven skin tone while providing support against environmental stressors.
Evidence-Based Efficacy
The efficacy of Vitamin C and its role in skin health has been supported by various studies. For more information, refer to the following studies: The Role of Inflammatory Biomarkers in Disease Severity and Treatment Response across Psoriasis, Atopic Dermatitis, and Hidradenitis Suppurativa-A Narrative Review and Advancing Precision Medicine in Inflammatory Skin Disease.
NeoStrata Skin Active FIRMING Potent Retinol Complex
NeoStrata Skin Active FIRMING Potent Retinol Complex
This potent Retinol night serum minimises the potential for irritation associated with Retinol with nourishing Centella Asiatica and hydrating Hyaluronic Acid. The result is smoother, more even-looking skin.
Key Benefits:
- 0.3% Pure Retinol: A powerful antioxidant that promotes skin turnover, reducing the appearance of fine lines, wrinkles, and sun damage.
- 4% Niacinamide: Helps to fade age spots and promote a brighter, more even skin tone.
- 2% NeoGlucosamine: Visibly firms skin while gently exfoliating to improve the appearance of photoaged skin.
- Centella Asiatica: Soothes and balances reactive skin, protecting against environmental aggressors.
- Hyaluronic Acid: Delivers intense hydration, plumping the skin for a youthful appearance.
Clinical Results:
- After 8 weeks, 97% of participants noted firmer skin, and 92% observed less noticeable wrinkles and fading age spots.
- After 12 weeks, 97% reported a more even skin tone and lifted appearance.
Evidence-Based Efficacy
For more information on the efficacy of Retinol and its benefits, refer to the studies available on Europe PMC.
Safety & Application
Directions
Apply 3-4 drops to the palm of your hand. Using your fingertips, dab and smooth evenly over your face and neck. All iSClinical antioxidant formulations have been tested in final packaging and have been confirmed to remain stable and effective for 36 months, and up to 6 months after opening. L-ascorbic acid (pure vitamin C) is known to change color with time, however oxidation is minimal in SkinCeuticals antioxidant and the formulation is proven to remain effective. Science
Safety Notice
For external use only. Avoid contact with eyes. If irritation occurs, discontinue use.
Directions
In the evening, apply to clean skin once or twice weekly, working up to everyday as tolerated. Recommended for PM use. Follow with application of your favourite [NEOSTRATA](/brands/neostrata)® eye cream and moisturiser.
Safety Notice
Fragrance-free. Dermatologist & Allergy tested. Tested on all skin tones.


