iS Clinical Pro-Heal Serum Advance+
VersusSkinCeuticals Retinol 0.3

iS Clinical Pro-Heal Serum Advance+
Best For
All skin types, especially blemish-prone and sensitive skin.
Best For
Normal & Oily Skin
Ingredient Profiles
iS Clinical Pro-Heal Serum Advance+
Pro-Heal Serum Advance+ features our scientifically advanced L-Ascorbic Acid (Vitamin C), combined with a superior form of Olive Leaf Extract and pure Vitamins E and A. This powerful formulation significantly increases antioxidant protection while helping improve the appearance of compromised, blemish-prone, and aging skin. Clinical studies have shown that formulations containing L-Ascorbic Acid can significantly improve skin texture and reduce signs of aging. For more information, refer to the following studies: Enhancing Outcomes of Procedure Pairing With Next Generation Regenerating Skin Nectar With TriHex+ Technology and Transient immunostimulation with LPS promotes tissue repair in aged skin.
SkinCeuticals Retinol 0.3
SkinCeuticals Retinol 0.3 is a concentrated facial cream designed to improve the appearance of fine lines, wrinkles, discoloration, and blemishes. This potent nighttime cream features pure Retinol, enhanced with advanced stabilization and delivery technologies for a steady release. Formulated with Bisabolol to minimize irritation, it is packaged to preserve potency, making it suitable for those new to retinol. Research supports the efficacy of retinol in improving signs of skin aging. For instance, a study demonstrated that retinol significantly enhances skin hydration, firmness, and elasticity while reducing melanin levels and wrinkle depth.
Safety & Application
Directions
Apply 3-4 drops to the palm of hand. Using fingertips, dab and smooth evenly over face and neck. All iSClinical antioxidant formulations have been tested in final packaging and have been confirmed to remain stable and effective for 36 months, and up to 6 months after opening. L-ascorbic acid (pure vitamin C) is known to change color with time, however oxidation is minimal in SkinCeuticals antioxidant and the formulation is proven to remain effective. Science
Safety Notice
For external use only. Avoid contact with eyes. If irritation occurs, discontinue use.
Directions
In the evening, apply a pea-sized amount to clean, dry skin, avoiding the eye area. Allow product to absorb before applying other skincare products. Limit initial use to once or twice a week, gradually increasing frequency as tolerated.
Safety Notice
[Retinol](https://europepmc.org/article/PPR/PPR1179260) may increase photosensitivity. Always use a high-protection, broad-spectrum sunscreen when using this product. Not recommended for pregnant women or those intending to become pregnant.



